Martinsville man killed in off-road vehicle accident
30-year-old Jacob Mayes of Martinsville died Saturday night after losing control of his off-road vehicle near the 2200 block of Wilber Road, in Martinsville. Emergency Responders were called to the area around 9:45pm for an accident with serious injuries, and upon arrival, found Mayes suffering from critical injuries and he was later pronounced dead. An initial investigation into the crash shows that Mayes was driving the ORV when he lost control and was thrown off. He was not wearing a seatbelt or any safety devices, according to the Indiana Department of Natural Resources. The investigation into Mayes’ death is still active,
Lilly receives FDA Fast Track for Tirzepatide for treatment of adult obesity
Eli Lilly and Company announced that the US Food and Drug Administration (FDA) has granted Fast Track designation for the investigation of Tirzepatide for the treatment of adults with obesity, or overweight with weight-related comorbidities. The FDA grants Fast Track designation to facilitate the development and expedite the review of medicines to treat serious conditions and fill an unmet medical need. Fast Track designation is intended to bring promising medicines to patients sooner.
Based on discussions with the FDA, Lilly plans to initiate a rolling submission of a new drug application (NDA) for tirzepatide in adults with obesity or overweight this year, which when complete, will be based primarily on results from two Phase 3 clinical trials: SURMOUNT-1, which is complete, and SURMOUNT-2, which is expected to complete by the end of April 2023. The rolling submission allows Lilly to submit completed sections of an application for review by FDA, rather than wait until all sections are completed.
Assuming positive SURMOUNT-2 results, Lilly aims to complete the submission shortly after SURMOUNT-2 data is available. The Fast Track designation, along with a rolling submission, accelerates tirzepatide’s path to FDA submission.
There are no tricks here! Trunk or Treat at the Southside YMCA
All are welcome to attend this FREE, open-to-the-public event on Friday, October 28 from 6:00-8:00 pm. We invite everyone in the community to participate and bring their friends, family, and neighbors.
Vehicles will be set up in the parking lot near the soccer field at our Southeast Y. Snake through the parked cars to trunk-or-treat and cast your ballot for your favorite vehicle. Those who are only trunk-or-treating need not register. Simply show up and enjoy the spooky fun!
To reserve your spot as a parked car from which people can trunk-or-treat, please register online. You may register for as many vehicles as you would like! There will also be a “Best Decorated Vehicle” contest where everyone can cast their vote for their favorite vehicle.
This Week in Hoosier History
1811 – Robert Fulton’s “New Orleans” passed Madison, Indiana. It was the first steamboat on the Ohio River.
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